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A Multidisciplinary Analysis of Controversies in the by H. Ballentine Carter M.D., Donald S. Coffey Ph.D. (auth.),

By H. Ballentine Carter M.D., Donald S. Coffey Ph.D. (auth.), Donald S. Coffey, Martin I. Resnick, F. Andrew Dorr, James P. Karr (eds.)

These lawsuits emanate from the second one Prouts Neck convention on prostate melanoma hung on October 17-19, 1986, the topic of which was once deal with­ ment, with specialise in present concerns and destiny examine that's had to resolution serious questions on the topic of optimum administration of some of the phases of prostate melanoma. the target used to be to bare the main the most important difficulties impeding growth and to crystallize the mixed multidisci­ plinary enter generated by means of the convention into centred strategies or innovations for presentation to the nationwide melanoma Institute (NCI) , with the final word rationale of concentrating on examine to handle the concern matters pointed out. In organizing the workshop, each attempt was once made to keep up a multidisciplinary stability between nationally popular professionals on prostate melanoma. therefore, prime surgeons, radiation and scientific onco­ logists and biostatisticians have been in equivalent presence. whereas there have been lively exchanges with cautious scrutiny and critique of all information pre­ sented, there has been a typical trust that the problem of prostate melanoma will be most sensible approached during this multidisciplinary Organ Systems-oriented model. through the process the convention, it turned obvious to all current that significant nomenclature and procedural limitations have made it in general tough, and regularly most unlikely, to check result of medical research.

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Extra resources for A Multidisciplinary Analysis of Controversies in the Management of Prostate Cancer

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Though these specimens had substantial amounts of residual tumor, they were of lower grade and pathologic stage than Stage A2 tumors. Only 2 of these 5 Stage Al specimens had focal penetration of the capsule with none having seminal vesicle or lymph node involvement. All had a combined Gleason grade of ~ 5. In contrast, patients from our institution with Stage A2 disease have a 39 percent incidence of established capsular penetration, 22 percent chance of having seminal vesicle invasion and 9 percent risk of lymph node metastases (1).

33 41. 42. 43. H. A. Induction of prostatic adenocarcinomas in Lobund-Wistar rats by testosterone. The Prostate 3:563-568, 1982. Pollard, M. A. Promotional effects of testosterone and dietary fat on prostatic carcinogenesis in genetically susceptible rats. The Prostate 6:1-6, 1985. Pollard, M. H. Production of autochthmous prostate cancer in Lobund-Wistar rats by treatment with N-nitroso-Nmethy1urea and testosterone. J. Nat1. Cancer Inst. 77:538589, 1986. THE PROTO-BIOLOGY OF PROSTATE CANCER William A.

In this study, Sl percent of the patients who received endocrine therapy died of cardiovascular complications in comparison to 28 percent of the patients who did not receive endocrine therapy. Varkarakis attempted to separate Stage A patients based on the percent of resected tissue involved by tumor (17). Of the 9 patients with less than 4 percent tumor and the 2 patients with less than 12 percent tumor, 7 were alive without recurrence while 4 had died of other causes. Of the 20 patients with greater than 40 percent tumor, 2 experienced progression of their cancer.

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